Segrate to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Segrate and arrive at Avola every about 6 hours on average. If travelling with Trenitalia, you need to know the Segrate to Avola train schedule: the first train leaves at 18:00, while the last ride is at 19:29. A Segrate to Avola train cost about 122.85 €. But how long is the train ride from Segrate to Avola? Your journey takes about 19 hours on average.