Segrate to Venice trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Segrate and arrive at Venezia S. Lucia every 60 minutes on average. If travelling with Trenitalia, you need to know the Segrate to Venice train schedule: the first train leaves at 06:15, while the last ride is at 19:30. A Segrate to Venice train cost about 39.7 €. But how long is the train ride from Segrate to Venice? Your journey takes about 4 hours on average.