Senigallia to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Senigallia and arrive at Avola every about 4 hours on average. If travelling with Trenitalia, you need to know the Senigallia to Avola train schedule: the first train leaves at 17:02, while the last ride is at 21:02. A Senigallia to Avola train cost about 154.05 €. But how long is the train ride from Senigallia to Avola? Your journey takes about 20 hours on average.