Seregno to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Seregno to Alpignano train schedule: the first train leaves at 06:58, while the last ride is at 19:30. A Seregno to Alpignano train cost about 13.45 €. But how long is the train ride from Seregno to Alpignano? Your journey takes about 3 hours on average.