Seregno to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Enna every about 4 hours on average. If travelling with Trenitalia, you need to know the Seregno to Enna train schedule: the first train leaves at 17:30, while the last ride is at 19:30. A Seregno to Enna train cost about 123.8 €. But how long is the train ride from Seregno to Enna? Your journey takes about 9 hours on average.