Seregno to Milan trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Milano Centrale every 30 minutes on average. If travelling with Trenitalia, you need to know the Seregno to Milan train schedule: the first train leaves at 06:58, while the last ride is at 19:30. A Seregno to Milan train cost about 2.8 €. But how long is the train ride from Seregno to Milan? Your journey takes 20 minutes on average. Trenitalia offers 10 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Seregno to Milan and find low cost tickets starting from 2 €!