Seregno to Senigallia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Senigallia every 60 minutes on average. If travelling with Trenitalia, you need to know the Seregno to Senigallia train schedule: the first train leaves at 07:30, while the last ride is at 18:30. A Seregno to Senigallia train cost about 57.3 €. But how long is the train ride from Seregno to Senigallia? Your journey takes about 4 hours on average.