Seregno to Trapani trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Trapani every about 12 hours on average. If travelling with Trenitalia, you need to know the Seregno to Trapani train schedule: the first train leaves at 19:30, while the last ride is at 19:30. A Seregno to Trapani train cost about 75.2 €. But how long is the train ride from Seregno to Trapani? Your journey takes about 2 hours on average.