To get from Sesto Fiorentino a Casarano by train you can catch one of the 32 trains that everyday travel between Sesto Fiorentino and Lecce, the closest station to the city. For your trip from Sesto Fiorentino to Lecce by train you can choose to leave from one of Sesto Fiorentino main stations: Sesto Fiorentino, Salerno If travelling with Trenitalia, you need to know the Sesto Fiorentino to Lecce train schedule: the first train leaves at 06:48, while the last ride is at 21:36. A Sesto Fiorentino to Lecce train cost about 19.85 €. But how long is the train ride from Sesto Fiorentino to Lecce? Your journey takes about 9 hours on average.