Sesto San Giovanni to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sesto S. Giovanni and arrive at Ancona every 30 minutes on average. If travelling with Trenitalia, you need to know the Sesto San Giovanni to Ancona train schedule: the first train leaves at 06:29, while the last ride is at 13:16. A Sesto San Giovanni to Ancona train cost about 57.8 €. But how long is the train ride from Sesto San Giovanni to Ancona? Your journey takes about 5 hours on average.