Sesto San Giovanni to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sesto S. Giovanni and arrive at Avola every about 1 hour on average. If travelling with Trenitalia, you need to know the Sesto San Giovanni to Avola train schedule: the first train leaves at 07:48, while the last ride is at 19:27. A Sesto San Giovanni to Avola train cost about 110.65 €. But how long is the train ride from Sesto San Giovanni to Avola? Your journey takes about 20 hours on average.