Sesto San Giovanni to Tortona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sesto S. Giovanni and arrive at Tortona every 60 minutes on average. If travelling with Trenitalia, you need to know the Sesto San Giovanni to Tortona train schedule: the first train leaves at 06:23, while the last ride is at 23:00. A Sesto San Giovanni to Tortona train cost about 7.3 €. But how long is the train ride from Sesto San Giovanni to Tortona? Your journey takes about 2 hours on average. Trenitalia offers 1 direct trains between these two cities.