Sesto San Giovanni to Venice trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sesto S. Giovanni and arrive at Venezia S. Lucia every 60 minutes on average. If travelling with Trenitalia, you need to know the Sesto San Giovanni to Venice train schedule: the first train leaves at 06:29, while the last ride is at 18:46. A Sesto San Giovanni to Venice train cost about 39.3 €. But how long is the train ride from Sesto San Giovanni to Venice? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sesto San Giovanni to Venice and find low cost tickets starting from 23 €!