Sezze to Comiso trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Sezze to Comiso. Trains leave from Sezze Romano and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Sezze to Comiso train schedule: the first train leaves at 07:25, while the last ride is at 07:25. A Sezze to Comiso train cost about 73.15 €. But how long is the train ride from Sezze to Comiso? Your journey takes about 16 hours on average.