Sezze to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sezze Romano and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Sezze to Enna train schedule: the first train leaves at 07:25, while the last ride is at 22:37. A Sezze to Enna train cost about 66.45 €. But how long is the train ride from Sezze to Enna? Your journey takes about 12 hours on average.