Sezze to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Sezze to Messina. If travelling with Trenitalia, you need to know the Sezze to Messina train schedule: the first train leaves at 07:25, while the last ride is at 22:37. A Sezze to Messina train cost about 50.1 €. But how long is the train ride from Sezze to Messina? Your journey takes about 9 hours on average.