Sienna to Acireale trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Acireale every about 3 hours on average. If travelling with Trenitalia, you need to know the Sienna to Acireale train schedule: the first train leaves at 07:15, while the last ride is at 21:26. A Sienna to Acireale train cost about 79.2 €. But how long is the train ride from Sienna to Acireale? Your journey takes about 15 hours on average.