Sienna to Alessandria trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 17 daily rides to get from Sienna to Alessandria. Trains leave from Siena and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Alessandria train schedule: the first train leaves at 06:25, while the last ride is at 21:26. A Sienna to Alessandria train cost about 28.2 €. But how long is the train ride from Sienna to Alessandria? Your journey takes about 6 hours on average. Thanks to Trenitalia offers, you can save on your trip from Sienna to Alessandria and find prices starting from 34 €!