Sienna to Alpignano trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 13 daily rides to get from Sienna to Alpignano. Trains leave from Siena and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Alpignano train schedule: the first train leaves at 06:36, while the last ride is at 21:26. A Sienna to Alpignano train cost about 58.6 €. But how long is the train ride from Sienna to Alpignano? Your journey takes about 7 hours on average.