Sienna to Altamura trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Altamura every about 6 hours on average. If travelling with Trenitalia, you need to know the Sienna to Altamura train schedule: the first train leaves at 06:25, while the last ride is at 09:18. A Sienna to Altamura train cost about 126.8 €. But how long is the train ride from Sienna to Altamura? Your journey takes about 11 hours on average.