Sienna to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Avola every about 2 hours on average. If travelling with Trenitalia, you need to know the Sienna to Avola train schedule: the first train leaves at 08:18, while the last ride is at 21:26. A Sienna to Avola train cost about 93.9 €. But how long is the train ride from Sienna to Avola? Your journey takes about 20 hours on average.