Sienna to Ragusa trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Sienna to Ragusa. If travelling with Trenitalia, you need to know the Sienna to Ragusa train schedule: the first train leaves at 18:02, while the last ride is at 18:02. A Sienna to Ragusa train cost about 187.25 €. But how long is the train ride from Sienna to Ragusa? Your journey takes about 18 hours on average.