Sienna to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Ragusa every about 12 hours on average. If travelling with Trenitalia, you need to know the Sienna to Ragusa train schedule: the first train leaves at 18:02, while the last ride is at 18:02. A Sienna to Ragusa train cost about 187.25 €. But how long is the train ride from Sienna to Ragusa? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sienna to Ragusa and find low cost tickets starting from 77 €!