Sienna to Rosolini trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Sienna to Rosolini. If travelling with Trenitalia, you need to know the Sienna to Rosolini train schedule: the first train leaves at 17:43, while the last ride is at 21:26. A Sienna to Rosolini train cost about 93.35 €. But how long is the train ride from Sienna to Rosolini? Your journey takes about 18 hours on average.