Sienna to Treviglio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Treviglio every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Treviglio train schedule: the first train leaves at 06:36, while the last ride is at 19:41. A Sienna to Treviglio train cost about 70.0 €. But how long is the train ride from Sienna to Treviglio? Your journey takes about 5 hours on average.