Sienna to Vercelli trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Vercelli every about 1 hour on average. If travelling with Trenitalia, you need to know the Sienna to Vercelli train schedule: the first train leaves at 06:36, while the last ride is at 21:26. A Sienna to Vercelli train cost about 62.85 €. But how long is the train ride from Sienna to Vercelli? Your journey takes about 6 hours on average.