Sienna to Vicenza trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 24 daily rides to get from Sienna to Vicenza. Trains leave from Siena and arrive at Vicenza every 30 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Vicenza train schedule: the first train leaves at 07:02, while the last ride is at 21:26. A Sienna to Vicenza train cost about 37.75 €. But how long is the train ride from Sienna to Vicenza? Your journey takes about 5 hours on average. Thanks to Trenitalia offers, you can save on your trip from Sienna to Vicenza and find prices starting from 38 €!