Spoleto to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spoleto and arrive at Ancona every about 1 hour on average. If travelling with Trenitalia, you need to know the Spoleto to Ancona train schedule: the first train leaves at 06:12, while the last ride is at 22:26. A Spoleto to Ancona train cost about 9.6 €. But how long is the train ride from Spoleto to Ancona? Your journey takes about 3 hours on average. Trenitalia offers 6 direct trains between these two cities.