Spoleto to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spoleto and arrive at Caltanissetta Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Spoleto to Caltanissetta train schedule: the first train leaves at 05:15, while the last ride is at 19:00. A Spoleto to Caltanissetta train cost about 64.0 €. But how long is the train ride from Spoleto to Caltanissetta? Your journey takes about 16 hours on average.