Syracuse to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Caltanissetta Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Caltanissetta train schedule: the first train leaves at 06:32, while the last ride is at 17:16. A Syracuse to Caltanissetta train cost about 10.4 €. But how long is the train ride from Syracuse to Caltanissetta? Your journey takes about 4 hours on average.