Syracuse to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Mazara del Vallo every about 12 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Mazara del Vallo train schedule: the first train leaves at 07:20, while the last ride is at 07:20. A Syracuse to Mazara del Vallo train cost about 27.6 €. But how long is the train ride from Syracuse to Mazara del Vallo? Your journey takes about 10 hours on average.