Syracuse to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Messina train schedule: the first train leaves at 06:32, while the last ride is at 17:45. A Syracuse to Messina train cost about 9.7 €. But how long is the train ride from Syracuse to Messina? Your journey takes about 3 hours on average. Trenitalia offers 4 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Syracuse to Messina and find low cost tickets starting from 10 €!