Syracuse to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siracusa and arrive at Varese every about 12 hours on average. If travelling with Trenitalia, you need to know the Syracuse to Varese train schedule: the first train leaves at 10:25, while the last ride is at 10:25. A Syracuse to Varese train cost about 159.5 €. But how long is the train ride from Syracuse to Varese? Your journey takes about 22 hours on average.