Tolentino to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tolentino and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Tolentino to Syracuse train schedule: the first train leaves at 06:46, while the last ride is at 16:08. A Tolentino to Syracuse train cost about 74.0 €. But how long is the train ride from Tolentino to Syracuse? Your journey takes about 17 hours on average.