Tortona to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tortona and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Tortona to Caltanissetta train schedule: the first train leaves at 21:02, while the last ride is at 21:39. A Tortona to Caltanissetta train cost about 77.5 €. But how long is the train ride from Tortona to Caltanissetta? Your journey takes about 23 hours on average.