Tortona to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tortona and arrive at Castelvetrano every about 4 hours on average. If travelling with Trenitalia, you need to know the Tortona to Castelvetrano train schedule: the first train leaves at 21:02, while the last ride is at 21:39. A Tortona to Castelvetrano train cost about 119.45 €. But how long is the train ride from Tortona to Castelvetrano? Your journey takes about 12 hours on average.