Tortona to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Tortona to Messina. Trains leave from Tortona and arrive at Messina Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Tortona to Messina train schedule: the first train leaves at 07:26, while the last ride is at 21:39. A Tortona to Messina train cost about 106.4 €. But how long is the train ride from Tortona to Messina? Your journey takes about 15 hours on average. Trenitalia offers 1 direct trains between these two cities.