Tortona to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Tortona to Palermo. Trains leave from Tortona and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Tortona to Palermo train schedule: the first train leaves at 09:08, while the last ride is at 21:27. A Tortona to Palermo train cost about 113.3 €. But how long is the train ride from Tortona to Palermo? Your journey takes about 16 hours on average.