Tortona to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tortona and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Tortona to Syracuse train schedule: the first train leaves at 09:08, while the last ride is at 21:27. A Tortona to Syracuse train cost about 110.4 €. But how long is the train ride from Tortona to Syracuse? Your journey takes about 15 hours on average. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Tortona to Syracuse and find low cost tickets starting from 115 €!