Varese to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Varese and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the Varese to Palermo train schedule: the first train leaves at 17:36, while the last ride is at 17:36. A Varese to Palermo train cost about 113.1 €. But how long is the train ride from Varese to Palermo? Your journey takes about 18 hours on average.