Varese to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Varese and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Varese to Syracuse train schedule: the first train leaves at 15:36, while the last ride is at 17:36. A Varese to Syracuse train cost about 140.2 €. But how long is the train ride from Varese to Syracuse? Your journey takes about 17 hours on average.