Venice to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia S. Lucia and arrive at Mazara del Vallo every about 12 hours on average. If travelling with Trenitalia, you need to know the Venice to Mazara del Vallo train schedule: the first train leaves at 18:25, while the last ride is at 18:25. A Venice to Mazara del Vallo train cost about 232.2 €. But how long is the train ride from Venice to Mazara del Vallo? Your journey takes about 22 hours on average.