Vicenza to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Vicenza and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Vicenza to Castelvetrano train schedule: the first train leaves at 17:35, while the last ride is at 23:02. A Vicenza to Castelvetrano train cost about 132.65 €. But how long is the train ride from Vicenza to Castelvetrano? Your journey takes about 18 hours on average.