Vicenza to Comiso trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 6 daily rides to get from Vicenza to Comiso. Trains leave from Vicenza and arrive at Comiso every about 2 hours on average. If travelling with Trenitalia, you need to know the Vicenza to Comiso train schedule: the first train leaves at 15:02, while the last ride is at 23:02. A Vicenza to Comiso train cost about 112.7 €. But how long is the train ride from Vicenza to Comiso? Your journey takes about 18 hours on average.