Vicenza to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Vicenza and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Vicenza to Messina train schedule: the first train leaves at 07:05, while the last ride is at 23:02. A Vicenza to Messina train cost about 109.55 €. But how long is the train ride from Vicenza to Messina? Your journey takes about 14 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Vicenza to Messina and find low cost tickets starting from 59 €!