Brescia to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brescia and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Brescia to Messina train schedule: the first train leaves at 17:25, while the last ride is at 22:35. A Brescia to Messina train cost about 89.5 €. But how long is the train ride from Brescia to Messina? Your journey takes about 15 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Brescia to Messina and find low cost tickets starting from 61 €!