Brescia to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brescia and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Brescia to Syracuse train schedule: the first train leaves at 17:25, while the last ride is at 22:35. A Brescia to Syracuse train cost about 125.0 €. But how long is the train ride from Brescia to Syracuse? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Brescia to Syracuse and find low cost tickets starting from 59 €!