Brindisi to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Brindisi to Ancona train schedule: the first train leaves at 04:00, while the last ride is at 22:38. A Brindisi to Ancona train cost about 50.00 €. But how long is the train ride from Brindisi to Ancona? Your journey takes about 6 hours on average. Trenitalia offers 10 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Brindisi to Ancona and find low cost tickets starting from 19 €!