Brindisi to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Noto every about 4 hours on average. If travelling with Trenitalia, you need to know the Brindisi to Noto train schedule: the first train leaves at 07:49, while the last ride is at 20:38. A Brindisi to Noto train cost about 70.35 €. But how long is the train ride from Brindisi to Noto? Your journey takes about 23 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Brindisi to Noto and find low cost tickets starting from 68 €!