Brindisi to Sciacca trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi, Reggio di Calabria Centrale and arrive at Castelvetrano every about 2 hours on average. If travelling with Trenitalia, you need to know the Brindisi to Sciacca train schedule: the first train leaves at 07:49, while the last ride is at 20:38. A Brindisi to Sciacca train cost about 36.45 €. But how long is the train ride from Brindisi to Sciacca? Your journey takes about 4 hours on average.