Casale Monferrato to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casale Monferrato, Punta Raisi, Mozia-Birgi and arrive at Mazara del Vallo, Milano Centrale, Genova Sestri Ponente Aeroporto every 15 minutes on average. If travelling with Trenitalia, you need to know the Casale Monferrato to Mazara del Vallo train schedule: the first train leaves at 15:54, while the last ride is at 20:54. A Casale Monferrato to Mazara del Vallo train cost about 3 €. But how long is the train ride from Casale Monferrato to Mazara del Vallo? Your journey takes about 3 hours on average.